Tonix’s Tonmya Treats PTSD By Helping Sufferers Sleep Better


PTSD is a serious illness that has devastating symptoms. It affects 3.5% of American adults, or 8.6m individuals each year. The prevalence of PTSD is even higher among veterans.

The only FDA approved PTSD drug treatment, the SSRIs (selective serotonin reuptake inhibitors), failed to show efficacy in military-related PTSD and have serious side effects.

Tonix’s Tonmya is being studied in HONOR, a phase 3 trial for treating military-related PTSD. Tonmya works by improving sleep quality and allowing the mind to heal itself.

This article focuses on PTSD and discusses how Tonmya can meet a very important unmet medical need.

PTSD (post-traumatic stress disorder)

Trauma is a natural emotional response to extreme (negative) experiences that involve actual or threatened serious harm to oneself or others. However, for some, the memories of the traumatic events linger in the form of flashbacks and/or nightmares, and they are unable to recover fully. Sufferers of PTSD experience serious symptoms which can be acute or chronic. These symptoms include: re-experiencing (flashbacks, nightmares, frightening thoughts); avoidance (avoiding persons, places or situations); arousal and reactivity (being easily startled, feeling tense or on edge, having trouble sleeping, having angry outbursts); and cognition and mood symptoms (trouble remembering; negative thoughts about oneself and the world, loss of interest in activities once enjoyed). PTSD is a risk factor for depression, alcohol or substance abuse, absenteeism/unemployment, homelessness, violent acts, suicidal thoughts and suicides.

According to the National Institute of Mental Health, there are 3.5% of the adult population, or approximately 8.6 million individuals, suffering from PTSD each year. The lifetime prevalence for 13 to 18-year-olds is 4%.

The prevalence is much higher among veterans. In his paper entitled ‘Understanding Research on the Epidemiology of Trauma and PTSD,’ the author states:


Lifetime prevalence of PTSD among theater Veterans were 31% for men and 27% for women. Prevalence of PTSD was higher for those in the Army as opposed to other branches of the military. Diagnoses were more likely for those who served longer than 12 months and for those who entered the service between the ages of 17-19.’